All Notebooks | Help | Support | About
6th October 2011 @ 23:48
Repeat of MNR11-1 but following by TLC under 3 hours

MNR11-3%20scheme.png

MNR11-3%20table.PNG

Hazard and Risk Assessment:
As for MNR11-1

Procedure
MNR8-2 (130 mg, 0.28 mmol) was stirred with methanesulfonic acid (1.8 mL, 28 mmol) at 60°C and after 1 hour (first TLC) all the starting material had been consumed. The reaction was quenched with saturated sodium carbonate and extracted with EtOAc (20 mL x2). The organic fractions were dried over magnesium sulfate, filtered and concentrated under reduced pressure.

Crude:- 91 mgs as a dark orange oil
Linked Posts
This post is linked by:
Attached Files
MNR11-3 table.PNG
MNR11-3 scheme.png