All Notebooks | Help | Support | About
12th May 2012 @ 01:13
MW29-1-81.png
MW29-1-81, MW29-2, MW29-3N-Cyclohexanoyl-protection of the amine intermediate MW7-2-27 of PZQ (MW29-1 to MW29-3)
N-Cyclohexanoyl-protection of the amine intermediate MW7-2-27 of PZQ: Upscale (MW29-4)

MW28-1-80.png
MW28 Attempts to the acid-mediated Pictet-Spengler cyclization of MW14 (MW28-1-80)
MW36-2, -5 Optimizing conditions for the Ugi reaction (MW36-2 to MW36-5)

MW14-3-79.png
MW14-3 (MeO)2-derivative of PZQ: preparation of starting material (MW14-3-79)

MW39.png
MW39 Repeating the preparation of (+/-)-BINOL-N-triflyl phosphoramide (MW39-2)
Preparation of (+/-)-BINOL-N-triflyl phosphoramide (MW39)

MW38
Preparation of trifluoromethane sulfonamide (MW38)

MW40.png

MW40 Preparation of the dimethoxy ‘Ugi-intermediate’ via Ugi reaction (MW40)
MW36 Preparation of the Ugi-intermediate via Ugi reaction (MW36-1)
MW32-3 N-Cyclohexanoyl-protection of the amine intermediate MW14 of (MeO)2-PZQ (MW32)
MW32-1 N-Cyclohexanoyl-protection of the amine intermediate MW14 of (MeO)2-PZQ (MW32)

MW37.png
MW37 Preparation of 2-(3,4-Dimethoxyphenyl)ethyl isocyanide (MW37)



MW34.png

MW34 Scale-up - Preparation of 2-Phenylethyl isocyanide (MW34-2)
Preparation of 2-Phenylethyl isocyanide (MW34-1)

MW31.png

MW33

Cbz-protection of the amine intermediate of PZQ MW7-2-27 (MW33)

MW31-x.png

MW31 Attempts to the acid-mediated Pictet-Spengler cyclization of the ‘Ugi intermediate’ MW29 (MW31)

MW43.png

MW43 Repetition of the synthesis of N,N’-bis[3,5-bis(trifluoromethyl)phenyl]thiourea (MW43-2)

PZQ-Ph.png

Attempts to the Bronstedt-acid catalysed Pictet-Spengler cyclization using N,N’-bis[3,5-bis(trifluoromethyl)phenyl]thiourea (MW44)

MeO-PZQ-Ph.png

Attempts to the Bronstedt-acid catalysed Pictet-Spengler cyclization using N,N’-bis[3,5-bis(trifluoromethyl)phenyl]thiourea (MW44)

MeO-PZQ.png

Attempts to the Bronstedt-acid catalysed Pictet-Spengler cyclization using N,N’-bis[3,5-bis(trifluoromethyl)phenyl]thiourea (MW44)






Attached Files
MW28-1-80.png
MW14-3-79.png
MW29-1-81.png
MW39.png
MW40.png
MW37.png
MW34.png
MW31.png
MW31-x.png
MW43.png
PZQ-Ph.png
MeO-PZQ-Ph.png
MeO-PZQ.png