This Post
PermalinkURI
URI Label
Revisions
Export:
XML (With Files)
PNG Image
Archives
April 2013 (2)October 2012 (2)
September 2012 (6)
August 2012 (22)
July 2012 (20)
June 2012 (4)
May 2012 (21)
April 2012 (12)
March 2012 (22)
February 2012 (19)
January 2012 (27)
December 2011 (7)
November 2011 (12)
October 2011 (16)
September 2011 (5)
March 2011 (3)
February 2011 (8)
August 2010 (3)
July 2010 (5)
June 2010 (14)
May 2010 (3)
Sections
Compound Index (2)Experiments (215)
Ongoing Experiments (16)
Mnr
11-20 (4)41-50 (15)
1-10 (4)
21-30 (2)
Sc
1-10 (5)Tools
Show/Hide QR CodeShow/Hide Keys
Repeat of MNR11-1 but at room temperature
Hazard and Risk Assessment:
As for MNR11-1
Procedure:
MNR8-2 (120 mg, 0.26 mmol) was stirred with methanesulfonic acid (1.7 mL, 26 mmol) at room temperature and after 1 hours (first TLC) all the starting material had been consumed. The reaction was quenched with saturated sodium carbonate and extracted with EtOAc (20 mL x2). The organic fractions were dried over magnesium sulfate, filtered and concentrated under reduced pressure.
Crude - 67 mgs as an off white foam (almost crystalline)
Hazard and Risk Assessment:
As for MNR11-1
Procedure:
MNR8-2 (120 mg, 0.26 mmol) was stirred with methanesulfonic acid (1.7 mL, 26 mmol) at room temperature and after 1 hours (first TLC) all the starting material had been consumed. The reaction was quenched with saturated sodium carbonate and extracted with EtOAc (20 mL x2). The organic fractions were dried over magnesium sulfate, filtered and concentrated under reduced pressure.
Crude - 67 mgs as an off white foam (almost crystalline)
Linked Posts
This post is linked by:
Attached Files
MNR11-2 scheme.png
MNR1-2 table.PNG
MNR11-2 table.PNG